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butabarbital will lessen the level or effect of amlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.butabarbital will lower the extent or influence of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.Teniposide: Barbiturates may lessen the serum concentration of Teniposide. Admin